Death in hospital following ICU discharge: insights from the LUNG SAFE study

Abstract Background To determine the frequency of, and factors associated with, death in hospital following ICU discharge to ward. Methods The Large observational study UNderstand Global impact of Severe Acute respiratory FailurE was an international, multicenter, prospective cohort patients with severe failure, conducted across 459 ICUs from 50 countries globally. This aimed understand who survived their stay. We examined outcomes subpopulation discharged no limitations life sustaining treatments (‘treatment limitations’), subpopulations treatment limitations. Results 2186 (94%) survived, while 142 (6%) died hospital. 118 (61%) 77 (39%) Patients without that after were older, more likely have COPD, immunocompromise or chronic renal less trauma as a risk factor for ARDS. post receive neuromuscular blockade, any adjunctive measure, had higher pre- non-pulmonary SOFA score. A similar pattern seen discharge. Conclusions significant proportion die ICU, mortality life-sustaining place. Non-survivors systemic illness severity scores at than survivors. Trial Registration : ClinicalTrials.gov NCT02010073 .